Garca-Arieta Author information Article notes Copyright and License information Disclaimer Spanish Agency for Medicines and Health Care Products, CCampezo 1, Edificio 8, Planta 2A, 28022 Madrid, Spain A.Ĭopyright American Association of Pharmaceutical Scientists 2015 Abstract This regulatory note supports the previous findings that suggest that the software package Kinetica, up to version 5.0.10, provides incorrect results for the 90 confidence intervals for the ratio testreference where the groups are imbalanced in 2 2 crossover designs and parallel designs. Kinetica 5.0 Software License Information Disclaimer Garca-Arieta Spanish Agency for Medicines and Health Care Products, CCampezo 1, Edificio 8, Planta 2A, 28022 Madrid, Spain Find articles by A. Morales-Alcelay Spanish Agency for Medicines and Health Care Products, CCampezo 1, Edificio 8, Planta 2A, 28022 Madrid, Spain Find articles by S. PMCID: PMC4476979 PMID: 25787313 On the Incorrect Statistical Calculations of the Kinetica Software Package in Imbalanced Designs S. Kinetica has been used only for the statistical analysis of 21 bioequivalence studies during all of these years. Kinetica 5.0 Software By wurrihonmi1984 Follow | Public
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